Abatement & Prevention of Bacterial Diseases

The UN World Health Organization reported that antibiotic resistant infections currently are the second cause of death worldwide and predicts that antibiotic resistance will be responsible for 10 million deaths per year by 2050 and a cumulative loss to the world’s GDP of $100 trillion if no adequate measures are undertaken. Hence, tackling antibiotic-resistant bacterial infections is one of the major societal challenges of this moment, and there is an urgent need for novel methods to control bacterial diseases.

At CMET, we investigate novel strategies to control (antibiotic resistant) bacterial infections by unravelling bacterial disease mechanisms and developing strategies to interfere with these mechanisms (antivirulence therapy). We also take into account the ecology of bacterial pathogens in order to develop strategies to prevent disease.